Support Immune Function with Vitamin D

Vitamin D is an essential vitamin important for healthy immune function. Most cells have receptors for vitamin D, enabling it to help modulate adaptive and innate immunity and inflammation. These actions can help enhance the immune system’s ability to respond to infection, allergy and autoimmunity.[1-4]

Vitamin D may also help protect against respiratory illness. A large study found that vitamin D reduced the risk of respiratory tract infections compared with placebo.[5]

[1] Pfeffer PE, Hawrylowicz CM. Vitamin D in asthma: mechanisms of action and considerations for clinical trials. Chest. 2018 May;153(5):1229-1239.

[2] Dankers W, et al. Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential. Front Immunol. 2016;7:697.

[3] Szymczak I, Pawliczak R. The active metabolite of vitamin D3 as a potential immunomodulator. Scand J Immunol. 2016 Feb;83(2):83-91.

[4] Arababadi MK, et al. Vitamin D and toll like receptors. Life Sci. 2018 Jun 15;203:105-111.

[5] Jolliffe DA, et al. Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials. Lancet Diabetes Endocrinol. 2021 May;9(5):276-292.